Methotrexate-Induced Septicemia With Severe Pancytopenia and Diffuse Cutaneous Ulcerative Lesions.

Authors :: Tiewsoh I
Dey B
Chhangte M
Lyngdoh M
Sathees V
Source :: Cureus [Cureus] 2021 Sep 17; Vol. 13 (9), pp. e18069. Date of Electronic Publication: 2021 Sep 17 (Print Publication: 2021).
Publication Year :: 2021
Abstract: Methotrexate, a folate antimetabolite and one of the first few anti-neoplastic drugs, is now a commonly used drug in the treatment of many inflammatory disorders ranging from diseases like rheumatoid arthritis to psoriasis. The life-threatening toxicity of methotrexate in inflammatory diseases is not commonly encountered. Here we report a case of life-threatening multiorgan failure from methotrexate toxicity, which was given for skin lesions suspected to be psoriasis.<br />Competing Interests: The authors have declared that no competing interests exist.<br /> (Copyright © 2021, Tiewsoh et al.)

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