Endothelial GTPCH (GTP Cyclohydrolase 1) and Tetrahydrobiopterin Regulate Gestational Blood Pressure, Uteroplacental Remodeling, and Fetal Growth.

Authors :: Chuaiphichai S
Yu GZ
Tan CMJ
Whiteman C
Douglas G
Dickinson Y
Drydale EN
Appari M
Zhang W
Crabtree MJ
McNeill E
Hale AB
Lewandowski AJ
Alp NJ
Vatish M
Leeson P
Channon KM
Source :: Hypertension (Dallas, Tex. : 1979) [Hypertension] 2021 Dec; Vol. 78 (6), pp. 1871-1884. Date of Electronic Publication: 2021 Oct 25.
Publication Year :: 2021
Abstract: [Figure: see text].

Subjects :: Animals
Biopterins genetics
Biopterins metabolism
Endothelium, Vascular metabolism
Extracellular Vesicles metabolism
Female
GTP Cyclohydrolase genetics
Humans
Mice
Mice, Knockout
Nitric Oxide Synthase Type III metabolism
Pregnancy
Biopterins analogs & derivatives
Blood Pressure physiology
Endothelial Cells metabolism
Fetal Development physiology
GTP Cyclohydrolase metabolism
Placenta metabolism
Uterus metabolism

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