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Clinicopathologic Characteristics and Patient Outcomes of Phyllodes Tumors: A Single Institution Experience.
- Source :
-
The American surgeon [Am Surg] 2021 Dec; Vol. 87 (10), pp. 1533-1538. Date of Electronic Publication: 2021 Oct 23. - Publication Year :
- 2021
-
Abstract
- Phyllodes tumors (PT) are rare fibroepithelial neoplasms that are classified as benign, borderline, or malignant. Patients with PT diagnosed between 2009 and 2019 were identified from a prospectively maintained single institutional database. 76 patients with PT were included; 47 (61.8%) were benign, 9 (11.8%) were borderline, and 20 (26.3%) were malignant. The mean age at diagnosis was 52. Surgical treatment of benign PT included excisional biopsy in 31 (66.0%) patients, segmental mastectomy in 15 (31.9%), and mastectomy in 1 (2.1%). Among patients with borderline PT, operative management was excisional biopsy in 4 (44.4%) and segmental mastectomy in 5 (55.6%). Of those with malignant PT, 7 (35.0%) were treated with excisional biopsy alone, 9 (45.0%) had lumpectomy (segmental mastectomy), and 4 (20.0%) underwent mastectomy. Malignant PT had a higher rate of necrosis compared to borderline or benign PT (25.0% vs 0% vs 4.3%, P = .016). Four patients had recurrent PT. Final positive margins were associated with recurrence ( P = .044). The median overall follow-up time was 86.3 months (range 1.5-1414.1 months), and no deaths occurred among patients with malignant PT. Overall, recurrence rates of PT are low but may be increased by presence of positive margins.
- Subjects :
- Adult
Aged
Aged, 80 and over
Biopsy, Large-Core Needle
Breast Neoplasms mortality
Breast Neoplasms surgery
Female
Humans
Margins of Excision
Mastectomy methods
Middle Aged
Neoplasm Recurrence, Local
Phyllodes Tumor mortality
Phyllodes Tumor surgery
Retrospective Studies
Survival Rate
Breast Neoplasms pathology
Phyllodes Tumor pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1555-9823
- Volume :
- 87
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- The American surgeon
- Publication Type :
- Academic Journal
- Accession number :
- 34689588
- Full Text :
- https://doi.org/10.1177/00031348211051673