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A qualitative research study in Japan investigating patients' experience with metastatic castration-resistant prostate cancer: from diagnosis to decision for Ra-223 treatment.
- Source :
-
Future oncology (London, England) [Future Oncol] 2021 Dec; Vol. 17 (36), pp. 5103-5118. Date of Electronic Publication: 2021 Oct 19. - Publication Year :
- 2021
-
Abstract
- Aim: This qualitative study aimed to reveal symptoms and impacts among bone metastatic castration-resistant prostate cancer (or mCRPC) Japanese patients, prior to Radium-223 (Ra-223) treatment. Materials & Methods: Twenty-three mCRPC patients designated to receive Ra-223 and three treating physicians (Ra-223 prescribers) in Japan, were interviewed. All interview data were assessed for concept frequency, themes and saturation. Results: Forty-five percent of the patients (mean age: 75.8 years) were symptomatic at the time of enrollment. Interviews with all patients revealed 47 mCRPC symptoms, including back pain and bone-specific pain, and 45 life impacts, including worry about disease progression and the impact on daily, physical activities. Conclusion: The symptoms and impacts of living with mCRPC and the associated burden of bone metastasis and skeletal-related symptoms are varied and are important considerations for treatment.
- Subjects :
- Aged
Aged, 80 and over
Bone Neoplasms psychology
Bone Neoplasms secondary
Cost of Illness
Decision Making
Humans
Interviews as Topic
Japan
Male
Middle Aged
Physicians
Prostatic Neoplasms, Castration-Resistant pathology
Prostatic Neoplasms, Castration-Resistant psychology
Qualitative Research
Quality of Life
Radium therapeutic use
Bone Neoplasms diagnosis
Bone Neoplasms radiotherapy
Prostatic Neoplasms, Castration-Resistant diagnosis
Prostatic Neoplasms, Castration-Resistant radiotherapy
Subjects
Details
- Language :
- English
- ISSN :
- 1744-8301
- Volume :
- 17
- Issue :
- 36
- Database :
- MEDLINE
- Journal :
- Future oncology (London, England)
- Publication Type :
- Academic Journal
- Accession number :
- 34664992
- Full Text :
- https://doi.org/10.2217/fon-2021-0773