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68Ga-FAPI PET/CT Distinguishes the Reactive Lymph Nodes From Tumor Metastatic Lymph Nodes in a Patient With Nasopharyngeal Carcinoma.
- Source :
-
Clinical nuclear medicine [Clin Nucl Med] 2022 Apr 01; Vol. 47 (4), pp. 367-368. - Publication Year :
- 2022
-
Abstract
- Abstract: Accurate clinical staging is crucial for managing nasopharyngeal carcinoma (NPC). However, false-positive finding of cervical lymph nodes in 18F-FDG PET/CT and MRI may lead to unnecessary chemotherapy for NPC. In this case, we report a patient with NPC who was incorrectly diagnosed with bilateral cervical lymph node metastases by both 18F-FDG PET/CT and MRI. Subsequent pathology results showed proliferating lymphoid cells with no signs of tumor metastasis. Interestingly, no abnormal 68Ga-FAPI uptake was observed in the nonmetastatic reactive lymph nodes. Therefore, 68Ga-FAPI PET/CT may be useful for assessment of pretreatment lymph node status in NPC.<br />Competing Interests: Conflicts of interest and sources of funding: This report was funded by National Natural Science Foundation of China (grant number 82071961). The authors declare no conflicts of interest.<br /> (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)
- Subjects :
- Fluorodeoxyglucose F18
Humans
Lymph Nodes diagnostic imaging
Lymph Nodes pathology
Nasopharyngeal Carcinoma diagnostic imaging
Nasopharyngeal Carcinoma pathology
Quinolines
Nasopharyngeal Neoplasms diagnostic imaging
Nasopharyngeal Neoplasms pathology
Positron Emission Tomography Computed Tomography methods
Subjects
Details
- Language :
- English
- ISSN :
- 1536-0229
- Volume :
- 47
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Clinical nuclear medicine
- Publication Type :
- Academic Journal
- Accession number :
- 34653051
- Full Text :
- https://doi.org/10.1097/RLU.0000000000003939