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Endometriosis: Epidemiology, Classification, Pathogenesis, Treatment and Genetics (Review of Literature).
- Source :
-
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 29; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 29. - Publication Year :
- 2021
-
Abstract
- Endometriosis is a "mysterious" disease and its exact cause has not yet been established. Among the etiological factors, congenital, environmental, epigenetic, autoimmune and allergic factors are listed. It is believed that the primary mechanism of the formation of endometriosis foci is retrograde menstruation, i.e., the passage of menstrual blood through the fallopian tubes into the peritoneal cavity and implantation of exfoliated endometrial cells. However, since this mechanism is also observed in healthy women, other factors must also be involved in the formation of endometriosis foci. Endometriosis is in many women the cause of infertility, chronic pain and the deterioration of the quality of life. It also represents a significant financial burden on health systems. The article presents a review of the literature on endometriosis-a disease affecting women throughout the world.
- Subjects :
- Adult
Cyclooxygenase 2 metabolism
Cytokines metabolism
Endometriosis classification
Endometriosis epidemiology
Endometrium pathology
Female
Humans
Infertility, Female genetics
Vascular Endothelial Growth Factor A metabolism
Cyclooxygenase 2 genetics
Cytokines genetics
Endometriosis genetics
Endometrium metabolism
Gene Expression Regulation
Vascular Endothelial Growth Factor A genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1422-0067
- Volume :
- 22
- Issue :
- 19
- Database :
- MEDLINE
- Journal :
- International journal of molecular sciences
- Publication Type :
- Academic Journal
- Accession number :
- 34638893
- Full Text :
- https://doi.org/10.3390/ijms221910554