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The Ensembl COVID-19 resource: ongoing integration of public SARS-CoV-2 data.

Authors :
De Silva NH
Bhai J
Chakiachvili M
Contreras-Moreira B
Cummins C
Frankish A
Gall A
Genez T
Howe KL
Hunt SE
Martin FJ
Moore B
Ogeh D
Parker A
Parton A
Ruffier M
Sakthivel MP
Sheppard D
Tate J
Thormann A
Thybert D
Trevanion SJ
Winterbottom A
Zerbino DR
Finn RD
Flicek P
Yates AD
Source :
Nucleic acids research [Nucleic Acids Res] 2022 Jan 07; Vol. 50 (D1), pp. D765-D770.
Publication Year :
2022

Abstract

The COVID-19 pandemic has seen unprecedented use of SARS-CoV-2 genome sequencing for epidemiological tracking and identification of emerging variants. Understanding the potential impact of these variants on the infectivity of the virus and the efficacy of emerging therapeutics and vaccines has become a cornerstone of the fight against the disease. To support the maximal use of genomic information for SARS-CoV-2 research, we launched the Ensembl COVID-19 browser; the first virus to be encompassed within the Ensembl platform. This resource incorporates a new Ensembl gene set, multiple variant sets, and annotation from several relevant resources aligned to the reference SARS-CoV-2 assembly. Since the first release in May 2020, the content has been regularly updated using our new rapid release workflow, and tools such as the Ensembl Variant Effect Predictor have been integrated. The Ensembl COVID-19 browser is freely available at https://covid-19.ensembl.org.<br /> (© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.)

Details

Language :
English
ISSN :
1362-4962
Volume :
50
Issue :
D1
Database :
MEDLINE
Journal :
Nucleic acids research
Publication Type :
Academic Journal
Accession number :
34634797
Full Text :
https://doi.org/10.1093/nar/gkab889