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Echogenicity of Dupuytren's nodules is correlated to myofibroblast load and nodule hardness.
- Source :
-
The Journal of hand surgery, European volume [J Hand Surg Eur Vol] 2022 Mar; Vol. 47 (3), pp. 280-287. Date of Electronic Publication: 2021 Oct 07. - Publication Year :
- 2022
-
Abstract
- This study aimed to determine the association between the echogenicity of Dupuytren's disease nodules and myofibroblast load, and between echogenicity and nodule hardness. Thirty-eight nodules were assessed sonographically. The echogenicity of nodules was measured objectively with Image J (grey-value) and subjectively by visual inspection (hypo-, mixed and hyper-echogenicity). These findings were compared with myofibroblast load measured by histopathological analysis. In a different cohort, 97 nodules were assessed for grey-value and nodule hardness using a tonometer. There was a moderate, significant, negative association between grey-value and myofibroblast load and the subjective visual measurements corresponded to this finding. There was also a moderate, significant, negative association between grey-value and nodule hardness. Ultrasound and tonometry may be useful in the selection of patients for possible future preventive treatments.
Details
- Language :
- English
- ISSN :
- 2043-6289
- Volume :
- 47
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- The Journal of hand surgery, European volume
- Publication Type :
- Academic Journal
- Accession number :
- 34617826
- Full Text :
- https://doi.org/10.1177/17531934211050214