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Acute spontaneous subdural hematoma as an inaugural presentation of systemic lupus erythematosus with acquired factor XIII deficiency: a case report.
- Source :
-
The Pan African medical journal [Pan Afr Med J] 2021 Jul 21; Vol. 39, pp. 207. Date of Electronic Publication: 2021 Jul 21 (Print Publication: 2021). - Publication Year :
- 2021
-
Abstract
- Acute spontaneous subdural hematoma is a rare clinical situation. Among its various etiologies, underlying coagulopathy is associated with a considerable risk of mortality. A 43-year-old female patient with no comorbidity and no personal or family history of bleeding disorders, consulted for acute and intense headache. The brain computed tomography (CT) scan showed a compressive left fronto-parietal acute subdural hematoma. The cerebral magnetic resonance angiography and routine hemostasis workup were normal. Factor XIII activity was low at 41% and the etiological investigation was consistent with the diagnosis of systemic lupus erythematosus. Surgical evacuation of the hematoma, factor XIII supplementation and systemic corticosteroid therapy with hydroxy chloroquine resulted in a favorable outcome. Acquired factor XIII deficiency should be systematically investigated for any acute spontaneous subdural hematoma with a normal hemostasis assessment in an adult with no personal or family history of hemorrhage.<br />Competing Interests: The authors declare no competing interests.<br /> (Copyright: Tamba Marc Sandouno et al.)
- Subjects :
- Adult
Factor XIII Deficiency complications
Female
Headache etiology
Hematoma, Subdural, Acute etiology
Hematoma, Subdural, Acute therapy
Humans
Lupus Erythematosus, Systemic complications
Lupus Erythematosus, Systemic therapy
Magnetic Resonance Angiography
Tomography, X-Ray Computed
Factor XIII Deficiency diagnosis
Hematoma, Subdural, Acute diagnosis
Lupus Erythematosus, Systemic diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1937-8688
- Volume :
- 39
- Database :
- MEDLINE
- Journal :
- The Pan African medical journal
- Publication Type :
- Report
- Accession number :
- 34603588
- Full Text :
- https://doi.org/10.11604/pamj.2021.39.207.26336