Back to Search
Start Over
Kingella kingae Spondylodiscitis: Treatment Failure With Flucloxacillin.
- Source :
-
The Pediatric infectious disease journal [Pediatr Infect Dis J] 2022 Jan 01; Vol. 41 (1), pp. 48-50. - Publication Year :
- 2022
-
Abstract
- Kingella kingae infections generally respond well to most beta-lactam antibiotics. We investigated an antibiotic treatment failure in a 3-year-old with K. kingae L3-4 spondylodiscitis. Her disease progressed even after 19 days of high-dose intravenous flucloxacillin. The clinical isolate did not produce a beta-lactamase and despite phenotypic testing and whole-genome sequencing, the mechanism of flucloxacillin resistance remains unknown.<br />Competing Interests: The authors have no conflicts of interest to disclose.<br /> (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)
- Subjects :
- Child, Preschool
Female
Humans
Kingella kingae genetics
Neisseriaceae Infections diagnostic imaging
Neisseriaceae Infections microbiology
Spine diagnostic imaging
Spine microbiology
Tomography, X-Ray Computed
Treatment Failure
Treatment Outcome
Anti-Bacterial Agents therapeutic use
Discitis diagnosis
Discitis microbiology
Drug Resistance, Bacterial
Floxacillin therapeutic use
Kingella kingae drug effects
Neisseriaceae Infections drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1532-0987
- Volume :
- 41
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- The Pediatric infectious disease journal
- Publication Type :
- Academic Journal
- Accession number :
- 34596625
- Full Text :
- https://doi.org/10.1097/INF.0000000000003357