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Calculation of Aqueous Solubility of Organic Compounds.

Authors :
Tewari YB
Miller MM
Wasik SP
Source :
Journal of research of the National Bureau of Standards (1977) [J Res Natl Bur Stand (1977)] 1982 Mar-Apr; Vol. 87 (2), pp. 155-158.
Publication Year :
1982

Abstract

The aqueous solubility of 14 organic solutes has been calculated from their octanol/water partition coefficient and from their solute activity coefficient in octanol at infinite dilution. The solute activity coefficients were calculated from the Flory-Huggins and Hildebrand-Scatchard (FH-HS) equations and were found to be in good agreement with the activity coefficients determined from GC specific retention volume measurements. The calculated solubilities were in good agreement with the experimental solubilities.

Details

Language :
English
ISSN :
0160-1741
Volume :
87
Issue :
2
Database :
MEDLINE
Journal :
Journal of research of the National Bureau of Standards (1977)
Publication Type :
Academic Journal
Accession number :
34566077
Full Text :
https://doi.org/10.6028/jres.087.011