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Near-infrared light-responsive photothermal α-Fe 2 O 3 @Au/PDA core/shell nanostructure with on-off controllable anti-bacterial effects.
- Source :
-
Dalton transactions (Cambridge, England : 2003) [Dalton Trans] 2021 Oct 19; Vol. 50 (40), pp. 14235-14243. Date of Electronic Publication: 2021 Oct 19. - Publication Year :
- 2021
-
Abstract
- Antimicrobial materials are expected to be alternatives for antibiotics against multidrug-resistant bacteria. In this paper, non-spherical α-Fe <subscript>2</subscript> O <subscript>3</subscript> @Au/PDA core/shell nanoparticles with tunable shapes are synthesized by a one-step in situ oxidation-redox polymerization method toward near infrared light-responsive antibacterial therapy. The thickness and composition of the Au/PDA hybrid shell can be controlled by varying the concentration of HAuCl <subscript>4</subscript> and the dopamine precursor. Owing to the wonderful photothermal characteristics originating from the Au/PDA shell, the spindle α-Fe <subscript>2</subscript> O <subscript>3</subscript> @Au/PDA core shell nanoparticles exhibit excellent photothermal sterilization effects against both Escherichia coli and Staphylococcus aureus at low concentrations. Meanwhile, the NIR photothermal induced bactericidal performance indicates that α-Fe <subscript>2</subscript> O <subscript>3</subscript> @Au/PDA hybrid particles with tunable non-spherical shapes possess unique controllable antibacterial effects. As a result, this finding provides a simple strategy for fabricating high performance photothermal antibacterial agents and the final products possess high potential in synergistic antimicrobial therapy.
- Subjects :
- Anti-Bacterial Agents chemical synthesis
Anti-Bacterial Agents chemistry
Escherichia coli drug effects
Ferric Compounds chemistry
Gold chemistry
Indoles chemistry
Infrared Rays
Microbial Sensitivity Tests
Polymers chemistry
Staphylococcus aureus drug effects
Anti-Bacterial Agents pharmacology
Ferric Compounds pharmacology
Gold pharmacology
Indoles pharmacology
Nanostructures chemistry
Photothermal Therapy
Polymers pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 1477-9234
- Volume :
- 50
- Issue :
- 40
- Database :
- MEDLINE
- Journal :
- Dalton transactions (Cambridge, England : 2003)
- Publication Type :
- Academic Journal
- Accession number :
- 34550127
- Full Text :
- https://doi.org/10.1039/d1dt02251b