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Acinic cell carcinoma of the parotid gland with neuroendocrine differentiation.

Authors :
Rath A
Tomar R
Agarwal R
Singh M
Jain S
Khurana N
Rathore PK
Source :
Journal of cancer research and therapeutics [J Cancer Res Ther] 2021 Jul-Sep; Vol. 17 (4), pp. 1115-1118.
Publication Year :
2021

Abstract

Acinic cell carcinoma (ACC) is a malignant salivary gland tumor characterized by tumor cells displaying acinar features. Usually presenting as a slow-growing tumor, ACC, however, may show dedifferentiation to a higher grade including neuroendocrine carcinoma. In addition, ACC may rarely show focal neuroendocrine differentiation without any frank evidence of neuroendocrine carcinoma. We describe such a case of ACC of the parotid gland in a 65-year-old female, which showed neuroendocrine differentiation. The diagnostic clues, immunohistochemistry panel, and prognostic and treatment aspects are also presented.<br />Competing Interests: None

Details

Language :
English
ISSN :
1998-4138
Volume :
17
Issue :
4
Database :
MEDLINE
Journal :
Journal of cancer research and therapeutics
Publication Type :
Report
Accession number :
34528574
Full Text :
https://doi.org/10.4103/jcrt.JCRT_645_19