Scorpion-Derived Antiviral Peptides with a Special Focus on Medically Important Viruses: An Update.

Authors :: El Hidan MA
Laaradia MA
El Hiba O
Draoui A
Aimrane A
Kahime K
Source :: BioMed research international [Biomed Res Int] 2021 Sep 04; Vol. 2021, pp. 9998420. Date of Electronic Publication: 2021 Sep 04 (Print Publication: 2021).
Publication Year :: 2021
Abstract: The global burden of viral infection, especially the current pandemics of SARS-CoV-2, HIV/AIDS, and hepatitis, is a very risky one. Additionally, HCV expresses the necessity for antiviral therapeutic elements. Venoms are known to contain an array of bioactive peptides that are commonly used in the treatment of various medical issues. Several peptides isolated from scorpion venom have recently been proven to possess an antiviral activity against several viral families. The aim of this review is to provide an up-to-date overview of scorpion antiviral peptides and to discuss their modes of action and potential biomedical application against different viruses.<br />Competing Interests: The authors declare no conflict of interest.<br /> (Copyright © 2021 Moulay Abdelmonaim El Hidan et al.)

Subjects :: Animals
Coronavirus drug effects
HIV-1 drug effects
Hepatitis Viruses drug effects
Herpesvirus 1, Human drug effects
Humans
Measles virus drug effects
Peptides chemistry
Peptides isolation & purification
Virus Diseases virology
Antiviral Agents chemistry
Antiviral Agents pharmacology
Peptides pharmacology
Scorpion Venoms chemistry
Virus Diseases drug therapy

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