Longitudinally extensive transverse myelitis as a sign of multisystem inflammatory syndrome following COVID-19 infection: A pediatric case report.

Authors :: Pourmoghaddas Z
Sadeghizadeh A
Tara SZ
Zandifar A
Rahimi H
Saleh R
Ghazavi M
Yaghini O
Hosseini N
Javadi N
Saadatnia M
Vossough A
Source :: Journal of neuroimmunology [J Neuroimmunol] 2021 Nov 15; Vol. 360, pp. 577704. Date of Electronic Publication: 2021 Aug 28.
Publication Year :: 2021
Abstract: COVID-19 infection can cause inflammatory reactions that could involve several organs. In the pediatric population, Multi-System Inflammatory Syndrome in Children (MIS-C) has been reported as one of the consequences of COVID-19. We report a unique pediatric COVID-19 patient with MIS-C, associated with paralysis of the extremities. MRI showed abnormal signal in the cervical spinal cord compatible with transverse myelitis. Methylprednisolone and IVIG were administered, without significant symptom improvement. As a next step, Infliximab was tried for her, and she responded remarkably well to this treatment. Infliximab may be considered as a treatment option in COVID-19 patients with transverse myelitis.<br /> (Copyright © 2021 Elsevier B.V. All rights reserved.)

Subjects :: Antirheumatic Agents therapeutic use
COVID-19 diagnostic imaging
COVID-19 etiology
Child
Female
Humans
Infliximab therapeutic use
Myelitis, Transverse drug therapy
Systemic Inflammatory Response Syndrome drug therapy
COVID-19 Drug Treatment
COVID-19 complications
Myelitis, Transverse diagnostic imaging
Myelitis, Transverse etiology
Systemic Inflammatory Response Syndrome diagnostic imaging
Systemic Inflammatory Response Syndrome etiology

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