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Biology of COVID-19 and related viruses: Epidemiology, signs, symptoms, diagnosis, and treatment.
- Source :
-
Best practice & research. Clinical anaesthesiology [Best Pract Res Clin Anaesthesiol] 2021 Oct; Vol. 35 (3), pp. 269-292. Date of Electronic Publication: 2020 Dec 08. - Publication Year :
- 2021
-
Abstract
- Coronaviruses belong to the family Coronaviridae order Nidovirales and are known causes of respiratory and intestinal disease in various mammalian and avian species. Species of coronaviruses known to infect humans are referred to as human coronaviruses (HCoVs). While traditionally, HCoVs have been a significant cause of the common cold, more recently, emergent viruses, including severe acute respiratory syndrome coronavirus (SARS-CoV-2) has caused a global pandemic. Here, we discuss coronavirus disease (COVID-19) biology, pathology, epidemiology, signs and symptoms, diagnosis, treatment, and recent clinical trials involving promising treatments.<br />Competing Interests: Declaration of competing interest Richard D. Urman received unrelated funding or fees from Merck, Medtronic/Covidien, AcelRx, Heron and Pfizer. Alan D. Kaye received fees from Merck. Other authors report no conflicts of interest.<br /> (Copyright © 2020 Elsevier Ltd. All rights reserved.)
- Subjects :
- Adenosine Monophosphate administration & dosage
Adenosine Monophosphate analogs & derivatives
Adrenal Cortex Hormones administration & dosage
Alanine administration & dosage
Alanine analogs & derivatives
Animals
COVID-19 diagnosis
COVID-19 immunology
Coronavirus drug effects
Coronavirus immunology
Cough epidemiology
Cough therapy
Diabetes Mellitus epidemiology
Diabetes Mellitus therapy
Fatigue epidemiology
Fatigue therapy
Fever
Heart Diseases epidemiology
Heart Diseases therapy
Humans
Positive-Pressure Respiration methods
Prognosis
Pulmonary Disease, Chronic Obstructive epidemiology
Pulmonary Disease, Chronic Obstructive therapy
Treatment Outcome
Antiviral Agents administration & dosage
COVID-19 epidemiology
COVID-19 therapy
SARS-CoV-2 drug effects
SARS-CoV-2 immunology
Subjects
Details
- Language :
- English
- ISSN :
- 1878-1608
- Volume :
- 35
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Best practice & research. Clinical anaesthesiology
- Publication Type :
- Academic Journal
- Accession number :
- 34511219
- Full Text :
- https://doi.org/10.1016/j.bpa.2020.12.003