Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy.

Authors :: Baj A
Novazzi F
Pasciuta R
Genoni A
Ferrante FD
Valli M
Partenope M
Tripiciano R
Ciserchia A
Catanoso G
Focosi D
Maggi F
Source :: Emerging infectious diseases [Emerg Infect Dis] 2021 Dec; Vol. 27 (12), pp. 3180-3182. Date of Electronic Publication: 2021 Sep 09.
Publication Year :: 2021
Abstract: The Delta variant of concern of severe acute respiratory syndrome coronavirus 2 is dominant worldwide. We report a case cluster caused by Delta sublineage B.1.617.2 harboring the mutation E484K in Italy during July 11-July 29, 2021. This mutation appears to affect immune response and vaccine efficacy; monitoring its appearance is urgent.

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