Factitiously Elevated Total Triiodothyronine in a Euthyroid Patient with Multiple Myeloma.

Authors :: Mandal K
Ashorobi D
Lee A
Liao H
Kumar SC
Rosenthal DS
Source :: Case reports in endocrinology [Case Rep Endocrinol] 2021 Aug 30; Vol. 2021, pp. 8479193. Date of Electronic Publication: 2021 Aug 30 (Print Publication: 2021).
Publication Year :: 2021
Abstract: Sporadic reports of factitious elevations of thyroid hormones related to laboratory interference from autoantibodies and multiple myeloma paraproteins have appeared in the literature. Such clinically confusing laboratory results can lead to erroneous diagnoses and inappropriate treatments. We report an additional case of a patient with multiple myeloma and an IgG paraproteinemia who had such a spurious elevation of total T3 complicating her levothyroxine management of hypothyroidism. In addition, we alert clinicians that differences in performance characteristics between various manufacturers' test platforms may also cause spurious reports.<br />Competing Interests: The authors declare no conflicts of interest.<br /> (Copyright © 2021 Kaushik Mandal et al.)

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