Back to Search Start Over

The Use of Sunitinib as Maintenance Therapy in a Pediatric Patient With a Poorly Differentiated Thymic Carcinoma.

Authors :
Romanos-Sirakis E
Doan A
Bittman ME
Webb RL
Williamson AK
Edelman M
Hanson D
Riely GJ
Fein Levy C
Source :
Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2022 Mar 01; Vol. 44 (2), pp. e605-e608.
Publication Year :
2022

Abstract

Background: Thymic carcinomas are rare aggressive mediastinal tumors with a median survival of 2 years.<br />Observation: We present a pediatric patient who was diagnosed with metastatic thymic carcinoma and showed continuous improvement of his primary mass and lung metastases with a regimen of cisplatin/docetaxel followed by long-term maintenance therapy with sunitinib for over 5 years.<br />Conclusions: This report demonstrates a long-term positive treatment effect using chemotherapy followed by sunitinib in an advanced thymic carcinoma. We are not aware of other reports of pediatric patients with metastatic thymic carcinoma treated with sunitinib maintenance who maintained a durable response for this prolonged period of time.<br />Competing Interests: The authors declare no conflict of interest.<br /> (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)

Details

Language :
English
ISSN :
1536-3678
Volume :
44
Issue :
2
Database :
MEDLINE
Journal :
Journal of pediatric hematology/oncology
Publication Type :
Academic Journal
Accession number :
34486558
Full Text :
https://doi.org/10.1097/MPH.0000000000002312