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Factors Influencing the Prognosis of Patients with Intra-Abdominal Infection and Its Value in Assessing Prognosis.

Authors :
Pan J
Zhu Q
Zhang X
Xu J
Pan L
Mao X
Wu X
Source :
Infection and drug resistance [Infect Drug Resist] 2021 Aug 24; Vol. 14, pp. 3425-3432. Date of Electronic Publication: 2021 Aug 24 (Print Publication: 2021).
Publication Year :
2021

Abstract

Purpose: To explore the distribution of pathogenic bacteria in patients with intra-abdominal infection, to clarify the independent factors that affect the prognosis of patients with intra-abdominal infection and its evaluation value for prognosis.<br />Patients and Methods: The pathogens, underlying diseases, and related clinical data of patients with intra-abdominal infection from January 2012 to December 2019 in our hospital were retrospectively collected and the APACHE II score was calculated. The patients were divided into survival group and death group according to the prognosis, and the index between the two groups was compared. Spearman correlation analysis was used to evaluate the correlation between each index and prognosis, multivariate logistic regression analysis was used to screen the independent prognostic factors.<br />Results: Spearman correlation analysis showed that ALB level was negatively correlated with prognosis, age and APACHE II score were positively correlated with prognosis. Logistic regression analysis showed that age, ALB level, and APACHE II score were independent prognostic factors. The formula of age combined ALB level and APACHE II score was Y = X1-3.6X2 + 6.5X3 (X1 was the age, X2 was the ALB level and X3 was the APACHE II score), Y was positively correlated with poor prognosis, and the optimal cutoff value was Y = 40.96.<br />Conclusion: Age, ALB level, and APACHE II score are independent factors that influencing the prognosis of patients with intra-abdominal infection, and the combination of age, ALB level, and APACHE II score can better assess the prognosis of patients with intra-abdominal infection.<br />Competing Interests: The authors declare that they have no competing interests.<br /> (© 2021 Pan et al.)

Details

Language :
English
ISSN :
1178-6973
Volume :
14
Database :
MEDLINE
Journal :
Infection and drug resistance
Publication Type :
Academic Journal
Accession number :
34466008
Full Text :
https://doi.org/10.2147/IDR.S325386