Mutations Associated with SARS-CoV-2 Variants of Concern, Benin, Early 2021.

Authors :: Sander AL
Yadouleton A
de Oliveira Filho EF
Tchibozo C
Hounkanrin G
Badou Y
Adewumi P
René KK
Ange D
Sourakatou S
Sedjro E
Aïssi MAJ
Fidelia H
Djingarey MH
Nagel M
Jo WK
Moreira-Soto A
Drosten C
Landt O
Corman VM
Hounkpatin B
Drexler JF
Source :: Emerging infectious diseases [Emerg Infect Dis] 2021 Nov; Vol. 27 (11), pp. 2889-2903. Date of Electronic Publication: 2021 Aug 31.
Publication Year :: 2021
Abstract: Intense transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Africa might promote emergence of variants. We describe 10 SARS-CoV-2 lineages in Benin during early 2021 that harbored mutations associated with variants of concern. Benin-derived SARS-CoV-2 strains were more efficiently neutralized by antibodies derived from vaccinees than patients, warranting accelerated vaccination in Africa.