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Phosphaturic mesenchymal tumors: radiological aspects and suggested imaging pathway.

Authors :
Hussein MAM
Cafarelli FP
Paparella MT
Rennie WJ
Guglielmi G
Source :
La Radiologia medica [Radiol Med] 2021 Dec; Vol. 126 (12), pp. 1609-1618. Date of Electronic Publication: 2021 Aug 28.
Publication Year :
2021

Abstract

Phosphaturic mesenchymal tumors (PMTs) are rare mesenchymal neoplasms of soft tissue or bone origin that can give rise to a challenge in diagnostic imaging. These tumors are frequently associated with tumor-induced osteomalacia, also called oncogenic osteomalacia, which is a rare paraneoplastic syndrome characterized by ectopic secretion of fibroblast growth factor 23, a hormone that regulates serum phosphate level. PMTs show polymorphic features on both radiological findings and histological examination, causing problems in diagnosis owing to their similarity with other mesenchymal tumors. Thus, this paper aims to describe radiological aspects of PMTs and suggest an imaging pathway for accurate diagnosis throughout the evidence from the literature review.<br /> (© 2021. The Author(s).)

Details

Language :
English
ISSN :
1826-6983
Volume :
126
Issue :
12
Database :
MEDLINE
Journal :
La Radiologia medica
Publication Type :
Academic Journal
Accession number :
34453276
Full Text :
https://doi.org/10.1007/s11547-021-01412-1