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Biomedical Relevance of Novel Anticancer Peptides in the Sensitive Treatment of Cancer.
- Source :
-
Biomolecules [Biomolecules] 2021 Jul 29; Vol. 11 (8). Date of Electronic Publication: 2021 Jul 29. - Publication Year :
- 2021
-
Abstract
- The global increase in cancer mortality and economic losses necessitates the cautious quest for therapeutic agents with compensatory advantages over conventional therapies. Anticancer peptides (ACPs) are a subset of host defense peptides, also known as antimicrobial peptides, which have emerged as therapeutic and diagnostic candidates due to several compensatory advantages over the non-specificity of the current treatment regimens. This review aimed to highlight the ravaging incidence of cancer, the use of ACPs in cancer treatment with their mechanisms, ACP discovery and delivery methods, and the limitations for their use. This would create awareness for identifying more ACPs with better specificity, accuracy and sensitivity towards the disease. It would also promote their efficacious utilization in biotechnology, medical sciences and molecular biology to ease the severity of the disease and enable the patients living with these conditions to develop an accommodating lifestyle.
- Subjects :
- Amino Acid Sequence
Antimicrobial Cationic Peptides chemistry
Antimicrobial Cationic Peptides metabolism
Antineoplastic Agents chemistry
Antineoplastic Agents metabolism
Cell Line, Tumor
Cell Membrane chemistry
Cell Membrane metabolism
Drug Discovery methods
Humans
Neoplasms genetics
Neoplasms metabolism
Neoplasms pathology
Antimicrobial Cationic Peptides therapeutic use
Antineoplastic Agents therapeutic use
Cell Membrane drug effects
Molecular Targeted Therapy methods
Neoplasms drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 2218-273X
- Volume :
- 11
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Biomolecules
- Publication Type :
- Academic Journal
- Accession number :
- 34439786
- Full Text :
- https://doi.org/10.3390/biom11081120