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Biomedical Relevance of Novel Anticancer Peptides in the Sensitive Treatment of Cancer.

Authors :
Bakare OO
Gokul A
Wu R
Niekerk LA
Klein A
Keyster M
Source :
Biomolecules [Biomolecules] 2021 Jul 29; Vol. 11 (8). Date of Electronic Publication: 2021 Jul 29.
Publication Year :
2021

Abstract

The global increase in cancer mortality and economic losses necessitates the cautious quest for therapeutic agents with compensatory advantages over conventional therapies. Anticancer peptides (ACPs) are a subset of host defense peptides, also known as antimicrobial peptides, which have emerged as therapeutic and diagnostic candidates due to several compensatory advantages over the non-specificity of the current treatment regimens. This review aimed to highlight the ravaging incidence of cancer, the use of ACPs in cancer treatment with their mechanisms, ACP discovery and delivery methods, and the limitations for their use. This would create awareness for identifying more ACPs with better specificity, accuracy and sensitivity towards the disease. It would also promote their efficacious utilization in biotechnology, medical sciences and molecular biology to ease the severity of the disease and enable the patients living with these conditions to develop an accommodating lifestyle.

Details

Language :
English
ISSN :
2218-273X
Volume :
11
Issue :
8
Database :
MEDLINE
Journal :
Biomolecules
Publication Type :
Academic Journal
Accession number :
34439786
Full Text :
https://doi.org/10.3390/biom11081120