Rodent models used in preclinical studies of deep brain stimulation to rescue memory deficits.

Authors :: Faillot M
Chaillet A
Palfi S
Senova S
Source :: Neuroscience and biobehavioral reviews [Neurosci Biobehav Rev] 2021 Nov; Vol. 130, pp. 410-432. Date of Electronic Publication: 2021 Aug 23.
Publication Year :: 2021
Abstract: Deep brain stimulation paradigms might be used to treat memory disorders in patients with stroke or traumatic brain injury. However, proof of concept studies in animal models are needed before clinical translation. We propose here a comprehensive review of rodent models for Traumatic Brain Injury and Stroke. We systematically review the histological, behavioral and electrophysiological features of each model and identify those that are the most relevant for translational research.<br /> (Copyright © 2021 Elsevier Ltd. All rights reserved.)

Subjects :: Animals
Disease Models, Animal
Humans
Memory Disorders therapy
Rodentia
Brain Injuries, Traumatic therapy
Deep Brain Stimulation

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