Back to Search
Start Over
Recent Progress of SERS Nanoprobe for pH Detecting and Its Application in Biological Imaging.
- Source :
-
Biosensors [Biosensors (Basel)] 2021 Aug 19; Vol. 11 (8). Date of Electronic Publication: 2021 Aug 19. - Publication Year :
- 2021
-
Abstract
- As pH value almost affects the function of cells and organisms in all aspects, in biology, biochemical and many other research fields, it is necessary to apply simple, intuitive, sensitive, stable detection of pH and base characteristics inside and outside the cell. Therefore, many research groups have explored the design and application of pH probes based on surface enhanced Raman scattering (SERS). In this review article, we discussed the basic theoretical background of explaining the working mechanism of pH SERS sensors, and also briefly described the significance of cell pH measurement, and simply classified and summarized the factors that affected the performance of pH SERS probes. Some applications of pH probes based on surface enhanced Raman scattering in intracellular and extracellular pH imaging and the combination of other analytical detection techniques are described. Finally, the development prospect of this field is presented.
- Subjects :
- Humans
Hydrogen-Ion Concentration
Spectrum Analysis, Raman
Subjects
Details
- Language :
- English
- ISSN :
- 2079-6374
- Volume :
- 11
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Biosensors
- Publication Type :
- Academic Journal
- Accession number :
- 34436084
- Full Text :
- https://doi.org/10.3390/bios11080282