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[Cirrhotic cardiomyopathy].

Authors :
Kasper P
Steffen HM
Michels G
Source :
Deutsche medizinische Wochenschrift (1946) [Dtsch Med Wochenschr] 2021 Aug; Vol. 146 (16), pp. 1070-1076. Date of Electronic Publication: 2021 Aug 20.
Publication Year :
2021

Abstract

A cirrhotic cardiomyopathy (CCM) can be observed in patients with end-stage liver disease and is characterized by a systolic and/or diastolic dysfunction in the absence of pre-existing heart diseases. While the cardiac dysfunction is often masked at rest, it typically manifests itself during cardiovascular challenges such as hypovolemia, physical stress, or sepsis. The diagnosis of CCM is challenging and predominantly based on echocardiographic measurements to identify subclinical cardiac dysfunction. Additional diagnostic criteria include electrophysiological abnormalities such as QT-interval prolongation, an abnormal chronotropic or inotropic response to stress, elevated cardiac biomarkers such as natriuretic peptides, and structural cardiac abnormalities like left atrium enlargement. There is no specific therapy for CCM. Supportive measures and regular cardiac evaluation of high-risk patients and transplant candidates are important to reduce the risks associated with invasive procedures and treatments.<br />Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht.<br /> (Thieme. All rights reserved.)

Details

Language :
German
ISSN :
1439-4413
Volume :
146
Issue :
16
Database :
MEDLINE
Journal :
Deutsche medizinische Wochenschrift (1946)
Publication Type :
Academic Journal
Accession number :
34416775
Full Text :
https://doi.org/10.1055/a-1321-9523