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Endoscopic findings unrelated to portal hypertension in patients with liver cirrhosis undergoing a varicose vein screening programme.
- Source :
-
Gastroenterologia y hepatologia [Gastroenterol Hepatol] 2022 Jun-Jul; Vol. 45 (6), pp. 450-456. Date of Electronic Publication: 2021 Aug 14. - Publication Year :
- 2022
-
Abstract
- Aim: To determine the prevalence of endoscopic lesions unrelated with portal hypertension in patients with cirrhosis.<br />Patients and Methods: Cross-sectional study including a consecutive cohort of patients with liver cirrhosis enrolled in a screening program of oesophageal varices who underwent an upper gastrointestinal endoscopy from November, 2013, to November, 2018. Clinical predictors of endoscopic lesions unrelated to portal hypertension were analyzed by univariate and multivariate logistic regression.<br />Results: A total of 379 patients were included. The most frequent aetiology of liver disease was alcohol consumption (60.4%). The prevalence of endoscopic lesions unrelated with portal hypertension was 39.6% (n=150). Among 96 patients with peptic lesions, urease was obtained in 56.2% of patients (positive in 44.4% of them). The prevalence of endoscopic lesions unrelated to portal hypertension was not associated with age, gender, liver function or ultrasound findings of portal hypertension. The prevalence of endoscopic lesions unrelated to portal hypertension was not associated with age, gender, liver function or ultrasound findings of portal hypertension. Smokers had a trend to increased prevalence of endoscopic lesions unrelated to portal hypertension (43.2% vs. 34.6%; p=0.09), particularly peptic ulcer (6.4% vs. 0.6%; p=0.05) and peptic duodenitis (17.3% vs. 6.3%; p=0.002). Active smoking was the only independent predictor of peptic ulcer or duodenitis (OR=2.56; p=0.017).<br />Conclusion: Active smoking is a risk factor for endoscopic lesions unrelated to portal hypertension. This finding should be further investigated to reassess endoscopic screening programs in cirrhotic smokers.<br /> (Copyright © 2021 Elsevier España, S.L.U. All rights reserved.)
- Subjects :
- Cross-Sectional Studies
Endoscopy, Gastrointestinal adverse effects
Gastrointestinal Hemorrhage diagnostic imaging
Gastrointestinal Hemorrhage epidemiology
Gastrointestinal Hemorrhage etiology
Humans
Liver Cirrhosis complications
Liver Cirrhosis epidemiology
Liver Cirrhosis pathology
Portal Vein pathology
Duodenitis complications
Duodenitis pathology
Esophageal and Gastric Varices diagnostic imaging
Esophageal and Gastric Varices epidemiology
Esophageal and Gastric Varices etiology
Hypertension, Portal complications
Hypertension, Portal diagnostic imaging
Hypertension, Portal epidemiology
Peptic Ulcer complications
Varicose Veins complications
Varicose Veins pathology
Subjects
Details
- Language :
- English; Spanish; Castilian
- ISSN :
- 0210-5705
- Volume :
- 45
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Gastroenterologia y hepatologia
- Publication Type :
- Academic Journal
- Accession number :
- 34400186
- Full Text :
- https://doi.org/10.1016/j.gastrohep.2021.07.010