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[Research advance in multi-component pharmacokinetics of Chinese herbal extracts in recent five years].
- Source :
-
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2021 Jul; Vol. 46 (13), pp. 3270-3287. - Publication Year :
- 2021
-
Abstract
- The multi-component pharmacokinetic study of Chinese herbal extracts elaborates the in vivo processes,including absorption,distribution,metabolism,and excretion,of multiple bioactive components,which is of significance in revealing pharmacodynamic material basis of Chinese herbal medicine. In recent years,with the innovation in ideas,and development of techniques and methods on traditional Chinese medicine( TCM) research,the pharmacokinetic studies of Chinese herbal extracts were extensively performed,and notable progress has been made. This paper reviewed the advancement of multi-component pharmacokinetics of Chinese herbal extracts in recent five years from analysis technology of biological sample,the pharmacokinetic characteristics of Chinese herbal medicine with complex system,and the impacts of processing and pathological state on pharmacokinetics of Chinese herbal extracts,aiming to provide a reference for quality control,product development and rational medication of Chinese herbal extracts.
- Subjects :
- China
Humans
Medicine, Chinese Traditional
Quality Control
Drugs, Chinese Herbal
Subjects
Details
- Language :
- Chinese
- ISSN :
- 1001-5302
- Volume :
- 46
- Issue :
- 13
- Database :
- MEDLINE
- Journal :
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Publication Type :
- Academic Journal
- Accession number :
- 34396746
- Full Text :
- https://doi.org/10.19540/j.cnki.cjcmm.20210310.601