Back to Search Start Over

CBr 4 Mediated [4 + 1] Dehydrocyclization for the Synthesis of Functionalized Imidazo[1,5-a]heterocycles from Pyridin-2-ylmethanamines and Aldehydes.

Authors :
Wang Q
Zha M
Zhou F
Chen X
Wang B
Liu G
Qian L
Source :
ACS omega [ACS Omega] 2021 Aug 02; Vol. 6 (31), pp. 20303-20308. Date of Electronic Publication: 2021 Aug 02 (Print Publication: 2021).
Publication Year :
2021

Abstract

A CBr <subscript>4</subscript> mediated [4 + 1] dehydrocyclization was developed for the synthesis of imidazo[1,5-a]heterocycles from pyridin-2-ylmethanamines and aldehydes. This method was highly practical with the advantages of wide substrate scope, functional group tolerance, and mild reaction conditions.<br />Competing Interests: The authors declare no competing financial interest.<br /> (© 2021 The Authors. Published by American Chemical Society.)

Details

Language :
English
ISSN :
2470-1343
Volume :
6
Issue :
31
Database :
MEDLINE
Journal :
ACS omega
Publication Type :
Academic Journal
Accession number :
34395978
Full Text :
https://doi.org/10.1021/acsomega.1c02181