Long-term vasectomy effects on testis and accessory sex organ function in langur monkey.

Testicular biopsy, serum and semen samples from bilaterally vasectomized and sham-operated langur monkeys were studied following 1.5, 2.0 and 2.5 years of surgery to assess testis and accessory sex organ function. Testicular degeneration was evident in certain tubules. Circulating levels of serum testosterone were statistically unchanged. Seminal plasma concentrations of fructose, acid phosphatase, sodium and potassium did not change, whereas semen volume, LDH, magnesium and citric acid decreased significantly suggesting an altered prostatic function following longer durations of vasectomy.