Linking microbiota composition with antimalarial antibody response.

Authors :: Romoli O
Mancio-Silva L
Gendrin M
Source :: Trends in parasitology [Trends Parasitol] 2021 Oct; Vol. 37 (10), pp. 853-855. Date of Electronic Publication: 2021 Aug 11.
Publication Year :: 2021
Abstract: Microbiota composition recently arose as a factor correlating with malaria infection. Mandal et al. showed, via cecal transplant and antibacterial treatment, that the mouse microbiota modulates parasitemia by affecting spleen germinal centers where B cells are matured. They further identified correlations between microbiota composition and malaria severity in Ugandan children.<br />Competing Interests: Declaration of interests The authors declare no competing interests.<br /> (Copyright © 2021 Elsevier Ltd. All rights reserved.)