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Quantitative developmental biology in vitro using micropatterning.

Authors :
Blin G
Source :
Development (Cambridge, England) [Development] 2021 Aug 01; Vol. 148 (15). Date of Electronic Publication: 2021 Aug 03.
Publication Year :
2021

Abstract

Micropatterning encompasses a set of methods aimed at precisely controlling the spatial distribution of molecules onto the surface of materials. Biologists have borrowed the idea and adapted these methods, originally developed for electronics, to impose physical constraints on biological systems with the aim of addressing fundamental questions across biological scales from molecules to multicellular systems. Here, I approach this topic from a developmental biologist's perspective focusing specifically on how and why micropatterning has gained in popularity within the developmental biology community in recent years. Overall, this Primer provides a concise overview of how micropatterns are used to study developmental processes and emphasises how micropatterns are a useful addition to the developmental biologist's toolbox.<br />Competing Interests: Competing interests The authors declare no competing or financial interests.<br /> (© 2021. Published by The Company of Biologists Ltd.)

Details

Language :
English
ISSN :
1477-9129
Volume :
148
Issue :
15
Database :
MEDLINE
Journal :
Development (Cambridge, England)
Publication Type :
Academic Journal
Accession number :
34345912
Full Text :
https://doi.org/10.1242/dev.186387