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A phosphine-catalysed one-pot domino sequence to access cyclopentene-fused coumarins.

Authors :
Chen YS
Zheng Y
Chen ZJ
Xie ZZ
He XC
Xiao JA
Chen K
Xiang HY
Yang H
Source :
Organic & biomolecular chemistry [Org Biomol Chem] 2021 Aug 28; Vol. 19 (32), pp. 7074-7080. Date of Electronic Publication: 2021 Aug 03.
Publication Year :
2021

Abstract

A novel phosphine-catalysed, one-pot domino approach for the annulation of 2-formylphenyl alkynoates with activated methylene compounds to construct various cyclopentene-fused dihydrocoumarins is reported. This developed strategy provides a facile and efficient approach for the synthesis of structurally complex coumarins from inexpensive and readily available alkynoates.

Details

Language :
English
ISSN :
1477-0539
Volume :
19
Issue :
32
Database :
MEDLINE
Journal :
Organic & biomolecular chemistry
Publication Type :
Academic Journal
Accession number :
34342319
Full Text :
https://doi.org/10.1039/d1ob01143j