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Safety and Efficacy of Dermal Fillers in Patients With Connective Tissue Disease: A Review.
- Source :
-
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] [Dermatol Surg] 2021 Mar 01; Vol. 47 (3), pp. 360-364. - Publication Year :
- 2021
-
Abstract
- Background: Dermal fillers such as hyaluronic acid, poly-l-lactic acid, and polymethyl-methacrylate are often used to treat cutaneous defects such as lipoatrophy. However, concern exists regarding their use in patients with a connective tissue disease (CTD) because of a theoretical risk of disease reactivation or exacerbation. Evidence regarding their use in patients with CTD also remains limited.<br />Objective: This review intends to summarize and evaluate the available literature regarding the use of dermal fillers in patients with CTD.<br />Materials and Methods: A literature search until May 2020 was conducted through PubMed, Ovid MEDLINE, and Ovid Embase to identify articles discussing the treatment of cutaneous defects secondary to CTD. Articles discussing the use of autologous fat transfer alone were excluded.<br />Results: Twenty-three articles were reviewed. The amount of available evidence varies between the type of CTD and type of filler with morphea having the most published evidence out of the CTDs discussed and hyaluronic acid having the most published evidence out of the fillers discussed. Most studies demonstrated positive results with no report of disease reactivation or exacerbation.<br />Conclusion: Despite limited available evidence, dermal fillers seem to be safe as an adjunctive treatment for cutaneous defects in patients with CTD.<br /> (Copyright © 2021 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.)
- Subjects :
- Contraindications, Drug
Contraindications, Procedure
Disease Progression
Durapatite adverse effects
Durapatite therapeutic use
Humans
Hyaluronic Acid adverse effects
Hyaluronic Acid therapeutic use
Polyesters adverse effects
Polyesters therapeutic use
Polymethyl Methacrylate adverse effects
Polymethyl Methacrylate therapeutic use
Recurrence
Risk Factors
Connective Tissue Diseases
Cosmetic Techniques adverse effects
Dermal Fillers adverse effects
Dermal Fillers therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1524-4725
- Volume :
- 47
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
- Publication Type :
- Academic Journal
- Accession number :
- 34328288
- Full Text :
- https://doi.org/10.1097/DSS.0000000000002870