Comparison of the SARS-CoV-2 spike protein ELISA and the Abbott Architect SARS-CoV-2 IgG nucleocapsid protein assays for detection of antibodies.

Authors :: Wadhwa A
Yin S
Freeman B
Hershow RB
Killerby M
Yousaf AR
Lester S
Mills L
Buono SA
Pomeroy M
Owusu D
Chu VT
Tate JE
Bhattacharyya S
Hall P
Thornburg NJ
Kirking HL
Source :: PloS one [PLoS One] 2021 Jul 29; Vol. 16 (7), pp. e0255208. Date of Electronic Publication: 2021 Jul 29 (Print Publication: 2021).
Publication Year :: 2021
Abstract: Serologic assays developed for SARS-CoV-2 detect different antibody subtypes and are based on different target antigens. Comparison of the performance of a SARS-CoV-2 Spike-Protein ELISA and the nucleocapsid-based Abbott ArchitectTM SARS-CoV-2 IgG assay indicated that the assays had high concordance, with rare paired discordant tests results.<br />Competing Interests: The authors have declared that no competing interests exist.

Full Text Access

Tools