Back to Search
Start Over
Unusual presentations of a severe type 2 leprosy reaction mimicking sepsis induced by helminth infection.
- Source :
-
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Jul 27; Vol. 15 (7), pp. e0009453. Date of Electronic Publication: 2021 Jul 27 (Print Publication: 2021). - Publication Year :
- 2021
-
Abstract
- We describe an unusual case of type 2 leprosy reaction (T2R) with septic shock-like features induced by helminth infection in a 31-year-old Moluccan male patient with a history of completed treatment of WHO multidrug therapy (MDT)-multibacillary (MB) regimen 2 years before admission. During the course of illness, the patient had numerous complications, including septic shock, anemia, and disseminated intravascular coagulation (DIC). Nevertheless, antibiotic therapies failed to give significant results, and the source of infection could not be identified. Helminth infection was subsequently revealed by endoscopic examination followed by parasitological culture. Resolution of symptoms and normal level of organ function-specific markers were resolved within 3 days following anthelmintic treatment. This report demonstrated the challenge in the diagnosis and treatment of severe T2R. Given that helminth infections may trigger severe T2R that mimics septic shock, health professionals need to be aware of this clinical presentation, especially in endemic regions of both diseases.<br />Competing Interests: The authors have declared that no competing interests exist.
- Subjects :
- Adult
Animals
Helminthiasis etiology
Helminths classification
Helminths genetics
Helminths isolation & purification
Humans
Leprostatic Agents therapeutic use
Leprosy complications
Male
Opportunistic Infections etiology
Opportunistic Infections parasitology
Sepsis etiology
Helminthiasis parasitology
Leprostatic Agents adverse effects
Leprosy drug therapy
Sepsis parasitology
Subjects
Details
- Language :
- English
- ISSN :
- 1935-2735
- Volume :
- 15
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- PLoS neglected tropical diseases
- Publication Type :
- Academic Journal
- Accession number :
- 34314436
- Full Text :
- https://doi.org/10.1371/journal.pntd.0009453