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Dupilumab: An Opportunity to Unravel In Vivo Actions of IL-4 and IL-13 in Humans.

Authors :
Roesner LM
Bridgewood C
McGonagle D
Wittmann M
Source :
The Journal of investigative dermatology [J Invest Dermatol] 2021 Aug; Vol. 141 (8), pp. 1879-1881.
Publication Year :
2021

Abstract

The application of biologics in clinical practice allows immunological observations under real-life conditions. In a new article in the Journal of Investigative Dermatology, Bakker et al. (2021) use deep immune cell phenotyping to demonstrate how dupilumab acts in a targeted fashion on skin-homing T cells, the driver cells of atopic dermatitis.<br /> (Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1523-1747
Volume :
141
Issue :
8
Database :
MEDLINE
Journal :
The Journal of investigative dermatology
Publication Type :
Academic Journal
Accession number :
34303467
Full Text :
https://doi.org/10.1016/j.jid.2021.02.007