Effects of Treatment of Coronavirus Disease 2019 With Convalescent Plasma in 25 B-Cell-Depleted Patients.

Authors :: Gharbharan A
GeurtsvanKessel CH
Jordans CCE
Blaauw M
van der Klift M
Hassing RJ
Smits-Zwinkels M
Meertens M
van den Hout EC
de Man AM
Hageman I
Bogers S
van der Schoot CE
Swaneveld F
Anas AA
Rokx C
Rijnders BJA
Source :: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2022 Apr 09; Vol. 74 (7), pp. 1271-1274.
Publication Year :: 2022
Abstract: Twenty-five B-cell-depleted patients (24 following anti-CD19/20 therapy) diagnosed with coronavirus disease 2019 had been symptomatic for a median of 26 days but remained antibody negative. All were treated with convalescent plasma with high neutralizing antibody titers. Twenty-one (84%) recovered, indicating the potential therapeutic effects of this therapy in this particular population.<br /> (© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America.)

Subjects :: Antibodies, Neutralizing therapeutic use
Antibodies, Viral
Humans
Immunization, Passive
SARS-CoV-2
COVID-19 Serotherapy
COVID-19 therapy

Language :: English
ISSN :: 1537-6591
Volume :: 74
Issue :: 7
Database :: MEDLINE
Journal :: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Publication Type :: Academic Journal
Accession number :: 34293119
Full Text :: https://doi.org/10.1093/cid/ciab647

Full Text Access

Tools