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Globus Pallidus Internus Deep Brain Stimulation Using Frame-Based vs . Frameless Stereotaxy in Dystonia: A Single-Center Experience.
- Source :
-
Frontiers in neurology [Front Neurol] 2021 Jun 29; Vol. 12, pp. 643757. Date of Electronic Publication: 2021 Jun 29 (Print Publication: 2021). - Publication Year :
- 2021
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Abstract
- Objective: Bilateral globus pallidus internus deep brain stimulation (GPi-DBS) is an established and effective therapy for primary refractory dystonia. However, the comparison of frameless vs . frame-based DBS surgery technique is still controversial. This retrospective study aims to compare the clinical outcome of two GPi-DBS surgical techniques for patients affected by primary generalized or multi-segmental dystonia. Methods: For lead's stereotaxic placement, 10 patients underwent frame-based surgery and the other 10 subjects DBS surgery with a frameless technique. Clinical features were evaluated at baseline and 6 and 12 months after surgery by means of the Burke-Fahn-Marsden Dystonia Rating Scale. Results: Frame-based GPi-DBS and frameless stereotaxic group revealed a comparable clinical outcome with no surgical complications. Conclusions: Frameless technique is safe and well-tolerated by patients and showed similar effectiveness of the frame-based stereotaxic surgery during GPi-DBS for primary dystonia. Notably, it could be a valid alternative solution because of the great advantage in improving the patient's discomfort during awake surgery.<br />Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.<br /> (Copyright © 2021 Eleopra, Rinaldo, Devigili, Mondani, D'Auria, Golfrè Andreasi, Skrap and Lettieri.)
Details
- Language :
- English
- ISSN :
- 1664-2295
- Volume :
- 12
- Database :
- MEDLINE
- Journal :
- Frontiers in neurology
- Publication Type :
- Academic Journal
- Accession number :
- 34267717
- Full Text :
- https://doi.org/10.3389/fneur.2021.643757