Independent predictors of in-hospital and 1-year mortality rates in octogenarians with acute myocardial infarction.

Older age is known as a negative prognostic parameter in acute myocardial infarction (AMI) patients. In this study, we aimed to explore age-associated differences in treatment protocols, in-hospital and 1-year mortality. This cohort observational study included 277 consecutive AMI patients, separated into 2 groups according to whether their age was ≥80 years or not. We found that group I patients (aged ≥80 years) had a notably lower rate of percutaneous coronary intervention (PCI) performed ( P < 0.0001) and a notably higher in-hospital death rate ( P < 0.003). The multivariate logistic regression analysis found that three variables were independent predictors of in-hospital mortality: age ≥80 years ( P < 0.0001), LVEF <40% ( P < 0.0001), and Killip class ≥3 ( P < 0.0001). The 1-year death rate was again significantly higher in group I patients ( P < 0.001) and was independently predicted by the triple-vessel coronary artery disease ( P = 0.004) and an LVEF <40% at admission ( P = 0.001). The 1-year readmission rate was superior in group I ( P < 0.01) and independently predicted by an age ≥80 years ( P < 0.001), and an history of congestive heart failure ( P < 0.0001) or permanent atrial fibrillation ( P < 0.001). We concluded that patients aged ≥80 benefit less often from a PCI and have higher rates of in-hospital mortality, as well as of 1-year readmission and mortality rates.
Competing Interests: The authors declare no conflict of interest.
(© 2021 The Author(s). Published by IMR Press.)