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Real-world effectiveness of repeated ketamine infusions for treatment resistant depression during the COVID-19 pandemic.
- Source :
-
Psychiatry research [Psychiatry Res] 2021 Sep; Vol. 303, pp. 114086. Date of Electronic Publication: 2021 Jun 29. - Publication Year :
- 2021
-
Abstract
- Herein we evaluate the impact of COVID-19 restrictions on antidepressant effectiveness of intravenous (IV) ketamine in adults with treatment-resistant depression (TRD). We conducted a case series analysis of adults with TRD (n = 267) who received four ketamine infusions at an outpatient clinic in Ontario, Canada, during COVID-19 restrictions (from March 2020 - February 2021; n = 107), compared to patients who received treatment in the previous year (March 2019 - February 2020; n = 160). Both groups experienced significant and comparable improvements in depressive symptoms, suicidal ideation, and anxiety with repeated ketamine infusions. Effectiveness of IV ketamine was not attenuated during the COVID-19 period.<br /> (Copyright © 2021 Elsevier B.V. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1872-7123
- Volume :
- 303
- Database :
- MEDLINE
- Journal :
- Psychiatry research
- Publication Type :
- Academic Journal
- Accession number :
- 34246008
- Full Text :
- https://doi.org/10.1016/j.psychres.2021.114086