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Surveillance of West Nile virus infection in Kashgar Region, Xinjiang, China, 2013-2016.
- Source :
-
Scientific reports [Sci Rep] 2021 Jul 07; Vol. 11 (1), pp. 14010. Date of Electronic Publication: 2021 Jul 07. - Publication Year :
- 2021
-
Abstract
- West Nile virus (WNV) was first isolated in mainland China from mosquitoes in Jiashi County, Kashgar Region, Xinjiang in 2011, following local outbreaks of viral meningitis and encephalitis caused by WNV. To elaborate the epidemiological characteristics of the WNV, surveillance of WNV infection in Kashgar Region, Xinjiang from 2013 to 2016 were carried out. Blood and CSF samples from surveillance human cases, blood of domestic chicken, cattle, sheep and mosquitoes in Kashgar Region were collected and detected. There were human 65 WNV Immunoglobulin M (IgM) antibody positive cases by ELISA screening, 6 confirmed WNV cases by the plaque reduction neutralization test (PRNT) screening. These cases occurred mainly concentrated in August to September of each year, and most of them were males. WNV-neutralizing antibodies were detected in both chickens and sheep, and the positive rates of neutralizing antibodies were 15.5% and 1.78%, respectively. A total of 15,637 mosquitoes were collected in 2013-2016, with Culex pipiens as the dominant mosquito species. Four and 1 WNV-positive mosquito pools were detected by RT-qPCR in 2013 and 2016 respectively. From these data, we can confirm that Jiashi County may be a natural epidemic foci of WNV disease, the trend highlights the routine virology surveillance in WNV surveillance cases, mosquitoes and avian should be maintained and enhanced to provide to prediction and early warning of outbreak an epidemic of WNV in China.
- Subjects :
- Adolescent
Adult
Animals
Animals, Domestic virology
Child
Child, Preschool
China epidemiology
Culicidae virology
Enzyme-Linked Immunosorbent Assay
Female
Geography, Medical
History, 21st Century
Humans
Male
Middle Aged
Public Health Surveillance
Seroepidemiologic Studies
West Nile Fever diagnosis
West Nile Fever history
Young Adult
West Nile Fever epidemiology
West Nile Fever virology
West Nile virus
Subjects
Details
- Language :
- English
- ISSN :
- 2045-2322
- Volume :
- 11
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Scientific reports
- Publication Type :
- Academic Journal
- Accession number :
- 34234184
- Full Text :
- https://doi.org/10.1038/s41598-021-93309-2