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Peptides in BioNMR Research.
- Source :
-
Chimia [Chimia (Aarau)] 2021 Jun 30; Vol. 75 (6), pp. 505-507. - Publication Year :
- 2021
-
Abstract
- Heteronuclear NMR in combination with isotope labelling is used to study folding of polypeptides induced by metals in the case of metallothioneins, binding of the peptidic allosteric modulator ρ-TIA to the human G-protein coupled α <subscript>1b</subscript> adrenergic receptor, the development of therapeutic drugs that interfere with the biosynthesis of the outer membrane of Gram-negative bacteria, and a system in which protein assembly is induced upon peptide addition. NMR in these cases is used to derive precise structural data and to study the dynamics.
- Subjects :
- Humans
Peptides
Receptors, Adrenergic, alpha-1
Subjects
Details
- Language :
- English
- ISSN :
- 0009-4293
- Volume :
- 75
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Chimia
- Publication Type :
- Academic Journal
- Accession number :
- 34233813
- Full Text :
- https://doi.org/10.2533/chimia.2021.505