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Acute Retinal Necrosis as a presenting ophthalmic manifestation in COVID 19 recovered patients.

Authors :
Soni A
Narayanan R
Tyagi M
Belenje A
Basu S
Source :
Ocular immunology and inflammation [Ocul Immunol Inflamm] 2021 May 19; Vol. 29 (4), pp. 722-725. Date of Electronic Publication: 2021 Jul 06.
Publication Year :
2021

Abstract

Purpose : Infection by the SARS-CoV2 virus results in an immune dysregulated state which can predispose to reactivation of Herpes viruses. This report describes the development of Acute Retinal Necrosis (ARN) in two patients who had recovered from SARS-CoV2 infection. Methods: Observational report of two consecutive patients who presented with ARN after having recovered from SARS-CoV-2 infection. Results: Case 1 was a 5-year-old child with extensive peripheral necrotizing retinitis. Case 2 was a 61-year-old gentlemen with bilateral retinal detachment with sieve-like breaks and optic atrophy. Both patients had recovered from SARS- Cov-2 infection 1 month ago. PCR from vitreous sample of both patients was positive for Herpes simplex virus. Case 1 was treated with oral valacyclovir. Case 2 underwent surgery in both eyes for retinal detachment Conclusion: Immune dysregulation after COVID-19 infection can result in reactivation of herpesvirus and may lead to development of ARN.

Details

Language :
English
ISSN :
1744-5078
Volume :
29
Issue :
4
Database :
MEDLINE
Journal :
Ocular immunology and inflammation
Publication Type :
Academic Journal
Accession number :
34228583
Full Text :
https://doi.org/10.1080/09273948.2021.1938135