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Diagnostic Methods for Non-Falciparum Malaria.
- Source :
-
Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2021 Jun 17; Vol. 11, pp. 681063. Date of Electronic Publication: 2021 Jun 17 (Print Publication: 2021). - Publication Year :
- 2021
-
Abstract
- Malaria is a serious public health problem that affects mostly the poorest countries in the world, killing more than 400,000 people per year, mainly children under 5 years old. Among the control and prevention strategies, the differential diagnosis of the Plasmodium -infecting species is an important factor for selecting a treatment and, consequently, for preventing the spread of the disease. One of the main difficulties for the detection of a specific Plasmodium sp is that most of the existing methods for malaria diagnosis focus on detecting P. falciparum . Thus, in many cases, the diagnostic methods neglect the other non-falciparum species and underestimate their prevalence and severity. Traditional methods for diagnosing malaria may present low specificity or sensitivity to non-falciparum spp. Therefore, there is high demand for new alternative methods able to differentiate Plasmodium species in a faster, cheaper and easier manner to execute. This review details the classical procedures and new perspectives of diagnostic methods for malaria non-falciparum differential detection and the possibilities of their application in different circumstances.<br />Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.<br /> (Copyright © 2021 Gimenez, Marques, Regiart and Bargieri.)
Details
- Language :
- English
- ISSN :
- 2235-2988
- Volume :
- 11
- Database :
- MEDLINE
- Journal :
- Frontiers in cellular and infection microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 34222049
- Full Text :
- https://doi.org/10.3389/fcimb.2021.681063