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Bispecific T Cell Engagers for the Treatment of Multiple Myeloma: Achievements and Challenges.

Authors :
Alhallak K
Sun J
Jeske A
Park C
Yavner J
Bash H
Lubben B
Adebayo O
Khaskiah A
Azab AK
Source :
Cancers [Cancers (Basel)] 2021 Jun 08; Vol. 13 (12). Date of Electronic Publication: 2021 Jun 08.
Publication Year :
2021

Abstract

MM is the second most common hematological malignancy and represents approximately 20% of deaths from hematopoietic cancers. The advent of novel agents has changed the therapeutic landscape of MM treatment; however, MM remains incurable. T cell-based immunotherapy such as BTCEs is a promising modality for the treatment of MM. This review article discusses the advancements and future directions of BTCE treatments for MM.

Details

Language :
English
ISSN :
2072-6694
Volume :
13
Issue :
12
Database :
MEDLINE
Journal :
Cancers
Publication Type :
Academic Journal
Accession number :
34201007
Full Text :
https://doi.org/10.3390/cancers13122853