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New Advances in the Biosynthesis of Glycopeptide Antibiotics of the Vancomycin Type from Amycolatopsis mediterranei.

Authors :
Süssmuth RD
Pelzer S
Nicholson G
Walk T
Wohlleben W
Jung G
Source :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 1999 Jul 12; Vol. 38 (13-14), pp. 1976-1979.
Publication Year :
1999

Abstract

Linear biosynthesis products from balhimycin, a tricyclic glycopeptide antibiotic of the vancomycin type, were isolated from mutants of Amycolatopsis mediterranei. The structures of these intermediates, determined by NMR spectroscopy, give new impulses for the understanding of the vancomycin biosynthesis.<br /> (© 1999 WILEY‐VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.)

Details

Language :
English
ISSN :
1521-3773
Volume :
38
Issue :
13-14
Database :
MEDLINE
Journal :
Angewandte Chemie (International ed. in English)
Publication Type :
Academic Journal
Accession number :
34182662
Full Text :
https://doi.org/10.1002/(SICI)1521-3773(19990712)38:13/14<1976::AID-ANIE1976>3.0.CO;2-3