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More Than Effects in Skin: Ultraviolet Radiation-Induced Changes in Immune Cells in Human Blood.
- Source :
-
Frontiers in immunology [Front Immunol] 2021 Jun 10; Vol. 12, pp. 694086. Date of Electronic Publication: 2021 Jun 10 (Print Publication: 2021). - Publication Year :
- 2021
-
Abstract
- Cells of the skin and circulation are in constant two-way communication. Following exposure of humans to sunlight or to phototherapy, there are alterations in the number, phenotype and function of circulating blood cells. In this review, only data obtained from human studies are considered, with changes induced by UV radiation (UVR) exposure described for phagocytic leukocytes and peripheral blood mononuclear cells plus their component T and B cells, natural killer cells and dendritic cells. These immune modulations illustrate the potential of UVR to have therapeutic effects beyond the skin, and that sunlight exposure is an important environmental influence on human health.<br />Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.<br /> (Copyright © 2021 Hart and Norval.)
- Subjects :
- B-Lymphocytes immunology
B-Lymphocytes metabolism
B-Lymphocytes radiation effects
Dendritic Cells immunology
Dendritic Cells metabolism
Humans
Killer Cells, Natural immunology
Killer Cells, Natural metabolism
Killer Cells, Natural radiation effects
Leukocytes immunology
Leukocytes metabolism
Seasons
T-Lymphocytes immunology
T-Lymphocytes metabolism
T-Lymphocytes radiation effects
Ultraviolet Rays adverse effects
Ultraviolet Therapy adverse effects
Dendritic Cells radiation effects
Leukocytes radiation effects
Phototherapy adverse effects
Radiation Exposure adverse effects
Sunlight adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1664-3224
- Volume :
- 12
- Database :
- MEDLINE
- Journal :
- Frontiers in immunology
- Publication Type :
- Academic Journal
- Accession number :
- 34177957
- Full Text :
- https://doi.org/10.3389/fimmu.2021.694086