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Betaine hydrochloride addition in Bama mini-pig's diets during gestation and lactation enhances immunity and alters intestine microbiota of suckling piglets.
- Source :
-
Journal of the science of food and agriculture [J Sci Food Agric] 2022 Jan 30; Vol. 102 (2), pp. 607-616. Date of Electronic Publication: 2021 Jun 30. - Publication Year :
- 2022
-
Abstract
- Background: Maternal nutrition during gestation and lactation is essential for offspring's health. The present study aimed to investigate the effects of betaine hydrochloride addition to sow diets during gestation and lactation on suckling piglet's immunity and intestine microbiota composition. Forty Bama mini-pigs were randomly allocated into two groups and fed a basal diet (control group) and a basal diet supplemented with 3.50 kg ton <superscript>-1</superscript> betaine hydrochloride (betaine group) from day 3 after mating to day 21 of lactation. After 21 days of the delivery, 12 suckling piglets from each group with similar body weight were selected for sample collection.<br />Results: The results showed that maternal betaine hydrochloride addition decreased (P < 0.05) the plasma levels of interleukin (IL)-1β, IL-2, IL-6, and tumor necrosis factor-α in suckling piglets. Furthermore, dietary betaine hydrochloride addition in sow diets increased (P < 0.05) the villus height (VH) and VH to crypt depth ratio in the jejunum and ileum of suckling piglets. In the piglets' intestinal microbiota community, the relative abundances of Roseburia (P < 0.05) and Clostridium (P = 0.059) were lower in the betaine group compared to those in the control group. Moreover, betaine hydrochloride addition in sow diets decreased the colonic tyramine (P = 0.091) and skatole (P = 0.070) concentrations in suckling piglets.<br />Conclusion: Betaine hydrochloride addition in sow diets enhanced the intestinal morphology, improved immunity, and altered intestinal microbiota of suckling piglets. These findings indicated that betaine hydrochloride addition in sow diets during gestation and lactation will impact suckling piglets' health. © 2021 Society of Chemical Industry.<br /> (© 2021 Society of Chemical Industry.)
- Subjects :
- Animal Feed analysis
Animals
Animals, Newborn growth & development
Animals, Newborn immunology
Animals, Newborn microbiology
Bacteria classification
Bacteria genetics
Bacteria isolation & purification
Dietary Supplements analysis
Female
Interleukins blood
Lactation
Male
Maternal Nutritional Physiological Phenomena
Pregnancy
Swine
Swine, Miniature blood
Swine, Miniature immunology
Swine, Miniature microbiology
Tumor Necrosis Factor-alpha blood
Betaine metabolism
Gastrointestinal Microbiome
Swine, Miniature embryology
Subjects
Details
- Language :
- English
- ISSN :
- 1097-0010
- Volume :
- 102
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of the science of food and agriculture
- Publication Type :
- Academic Journal
- Accession number :
- 34151432
- Full Text :
- https://doi.org/10.1002/jsfa.11389