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CT findings of acute radiation-induced pneumonitis in breast cancer.
CT findings of acute radiation-induced pneumonitis in breast cancer.
- Source :
-
The British journal of radiology [Br J Radiol] 2021 Aug 01; Vol. 94 (1124), pp. 20200997. Date of Electronic Publication: 2021 Jun 16. - Publication Year :
- 2021
-
Abstract
- Objectives: To evaluate the CT findings of acute radiation pneumonitis (RP) in breast cancer patients undergoing post-operative radiotherapy, and to analyze clinicodosimetric factors associated with acute RP.<br />Methods: Between 2015 and 2017, 61 patients with breast cancer who underwent follow-up chest CT at 3 months after radiotherapy were analyzed. The degree of acute RP on CT was evaluated by the change of extent and scoring system (grade 0, no RP; Grade 1, ground-glass opacities (GGOs); Grade 2, GGOs and/or consolidations; Grade 3, clear focal consolidation; Grade 4, dense consolidation). The dosimetric parameters were calculated from the dose-volume histogram of RT.<br />Results: The acute RP on CT was scored as follows: Grade 0, in 37.7%, Grade 1 in 13.1%, Grade 2 in 44.3%, and Grade 3 in 4.9%. The median extent of RP in patients with Grades 1 to 3 was 6.2 ml (range, 0.2-95.9). There were no clinicodosimetric factors significantly associated with the presence of RP or its severity. One patient developed symptomatic RP.<br />Conclusion: This study showed no correlation between acute RP and clinicodosimetric factors, and acute RP based on CT findings were much more common than symptomatic RP.<br />Advances in Knowledge: CT findings of acute RP or extent of RP were not significantly related to clinicodosimetric factors in breast cancer patients.
Details
- Language :
- English
- ISSN :
- 1748-880X
- Volume :
- 94
- Issue :
- 1124
- Database :
- MEDLINE
- Journal :
- The British journal of radiology
- Publication Type :
- Academic Journal
- Accession number :
- 34111374
- Full Text :
- https://doi.org/10.1259/bjr.20200997